Medical and Graduate Student Teaching

Cancer Biology (RON230B): Introductory cancer biology course for third year medical students and graduate students. I taught the radiation and chemical carcinogenesis portion of this course.

Human Genetics (UPG/GEN 232): This course addresses the topics of segregation, genetic linkage, population genetics, multifactorial inheritance, biochemical genetics, cytogenetics, somatic cell genetics, clinical genetics, positional cloning and complex disease. I gave lectures on the mechanisms of genomic imprinting and X chromosome inactivation.

Mammalian Toxicology (PHR 254): This course covers the principles of toxicology as related to humans. Emphasis is on the molecular basis for toxicity of chemical and physical agents. Subjects include metabolism and toxicokinetics, toxicologic evaluation, toxic agents, target organs, toxic effects, environmental toxicity, management of poisoning, epidemiology, risk assessment and regulatory toxicology. I taught the radiation and chemical carcinogenesis portion of this course.

Molecular Aspects of Disease (PTH 385): This course discusses the investigative methods and recent advances made in understanding the molecular basis of selected diseases. This course focuses on a small number of diseases whose defects are known at the genetic or molecular levels, and stresses integrative approaches to the study of human biology and disease. I teach the section on epigenetics and genomic imprinting in disease susceptibility.

Research in Pathology (PTH357): This course provides the opportunity for medical students to study special problems in pathology with a member of the senior faculty. Six students have done independent research in my laboratory, and I had one M.D./Ph.D. student in my laboratory.

Medical Residents

A course is provided each year to teach the radiology residents (diagnostic and therapeutic) radiation biology. I teach the sections in this course on radiation carcinogenesis, the physical factors that affect the radiosensitivity of cells, and the role of epigenetics and genomic imprinting in caner.

Undergraduate Students

I participate in a research training program which enables undergraduate students to do research in a laboratory. I have had five students who have each performed 2 yr of research in my laboratory. Two of these students completed their senior honors thesis work in my laboratory.

High School Students

The Duke University Cancer Center has a summer program since 1989 where high school students are given an opportunity to do laboratory research in the laboratory of a Cancer Center member. I have had 3 students in my laboratory from this program. The School of Science and Math in Durham, NC also has a program where a senior high school student can elect to spend 4 hr/wk in a university research laboratory. I have had 1 student from this program in my laboratory.